How Low Testosterone Can Affect Cognition

Testosterone is a hormone that plays a significant role in the human body. Both male and females need certain levels of testosterone in order to be healthy. Beyond its function in physical characteristics, it also plays a vital role in cognition and brain function, especially in males. Unfortunately, there are circumstances that may cause low testosterone which can have unwanted side effects, including changes in cognitive abilities. In this blog post, we will explore how low testosterone levels can affect cognition in people who are biologically male.


The Role of Testosterone in the Brain

Testosterone, a steroid hormone, is primarily produced in the testes but is also present, to a lesser extent, in ovaries. In men, it is responsible for the development of physical characteristics, but it also plays a critical role in the brain. Testosterone receptors are present in various brain regions, including the hippocampus, prefrontal cortex, and amygdala, all of which are vital for cognitive processes and health.

Causes of Low Testosterone

Low testosterone can occur due to a number of factors. Age is the leading contributor to lower levels. As men age, their body gradually tends to produce less testosterone. This is a natural process and unless it comes along with troublesome symptoms, is not a cause for worry.

Other leading causes of low testosterone include: 

  • Strong medicines such as chemotherapy
  • Thyroid conditions
  • Chronic disease
  • Testicle injury or cancer
  • PTSD 
  • Stress 
  • Adrenal Fatigue 
  • Hormone disrupting chemicals 

Impact of Low Testosterone on Cognition


One of the potential effects of low testosterone on cognition is its impact on memory. Studies have shown that men with lower testosterone levels may experience some level of difficulty with spatial and verbal memory. In a study, participants who received testosterone replacement therapy (TRT) experienced improvement in these memory skills. Deficits in memory could result in decreased efficiency in everyday tasks, affecting both personal and professional life.

Executive Functions

Executive functions are cognitive processes that help individuals plan, organize, and manage their behavior to achieve specific goals. Some of the essential executive functions include decision-making, problem-solving, and impulse control. Low testosterone levels have been linked to decreased executive function performance, leading to difficulties in making complex decisions and controlling emotions.

Mood and Social Cognition

Testosterone levels can also influence mood and emotional well-being. Research indicates that low testosterone levels are associated with an increased risk of depression. Males with low testosterone may also experience mood swings and irritability, which could impact their ability to regulate emotions and behavior, and therefore the ability to socialize effectively.

Treatment Options

The good news is that low testosterone and its cognitive effects are often treatable. If you suspect you might be experiencing cognitive changes due to low testosterone levels, we recommend consulting a healthcare professional. A simple blood test can determine your testosterone levels, and if necessary, various treatments are available, including TRT. However, it is essential to consult a qualified physician before embarking on any treatment, as individual circumstances may vary.


Low testosterone levels can impact cognition, affecting memory, executive functions, and mood in individuals who are biologically male. Understanding the role of testosterone in cognitive processes is crucial to recognizing and addressing cognitive changes that may be linked to hormonal imbalances. By seeking professional advice and exploring appropriate treatments, men can improve their cognitive function and overall quality of life, mitigating the impact of low testosterone on their well-being. We can all strive to foster a better understanding of the intricate relationship between hormones and cognitive function.

Aly Castle

Aly is HappyNeuron Pro’s Content Specialist. She is passionate about mental health and well-being and loves utilizing her design background to share important cognitive information clearly and understandably.

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